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Novel Ex Vivo Culture Method for the Study of Dupuytren's Disease: Effects of TGFβ Type 1 Receptor Modulation by Antisense Oligonucleotides
Dupuytren's disease (DD) is a benign fibroproliferative disease of the hand. It is characterized by the excessive production of extracellular matrix (ECM) proteins, which form a strong fibrous tissue between the handpalm and fingers, permanently disrupting the fine movement ability. The major c...
Autores principales: | Karkampouna, Sofia, Kruithof, Boudewijn PT, Kloen, Peter, Obdeijn, Miryam C, van der Laan, Annelies MA, Tanke, Hans J, Kemaladewi, Dwi U, Hoogaars, Willem MH, ‘t Hoen, Peter AC, Aartsma-Rus, Annemieke, Clark, Ian M, ten Dijke, Peter, Goumans, Marie-José, Kruithof-de Julio, Marianna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912325/ https://www.ncbi.nlm.nih.gov/pubmed/24448195 http://dx.doi.org/10.1038/mtna.2013.69 |
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