An integrated systems genetics screen reveals the transcriptional structure of inherited predisposition to metastatic disease

Metastasis is the result of stochastic genomic and epigenetic events leading to gene expression profiles that drive tumor dissemination. Here we exploit the principle that metastatic propensity is modified by the genetic background to generate prognostic gene expression signatures that illuminate re...

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Detalles Bibliográficos
Autores principales: Faraji, Farhoud, Hu, Ying, Wu, Gang, Goldberger, Natalie E., Walker, Renard C., Zhang, Jinghui, Hunter, Kent W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912413/
https://www.ncbi.nlm.nih.gov/pubmed/24322557
http://dx.doi.org/10.1101/gr.166223.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912413/
https://www.ncbi.nlm.nih.gov/pubmed/24322557
http://dx.doi.org/10.1101/gr.166223.113

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