Bitter melon extract attenuating hepatic steatosis may be mediated by FGF21 and AMPK/Sirt1 signaling in mice

We sought to evaluate the effects of Momordica charantia (bitter melon, BM) extract on insulin sensitivity, NAFLD, hepatic FGF21 and AMPK signaling in mice fed a high-fat diet. Male C57/B6 mice were randomly divided into HFD and HFD supplementation with BM for 12 week. Body weight, plasma glucose, F...

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Detalles Bibliográficos
Autores principales: Yu, Yongmei, Zhang, Xian H., Ebersole, Blake, Ribnicky, David, Wang, Zhong Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912441/
https://www.ncbi.nlm.nih.gov/pubmed/24189525
http://dx.doi.org/10.1038/srep03142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912441/
https://www.ncbi.nlm.nih.gov/pubmed/24189525
http://dx.doi.org/10.1038/srep03142

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