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Inflammation induced by mast cell deficiency rather than the loss of interstitial cells of Cajal causes smooth muscle dysfunction in W/W(v) mice

The initial hypothesis suggested that the interstitial cells of Cajal (ICC) played an essential role in mediating enteric neuronal input to smooth muscle cells. Much information for this hypothesis came from studies in W/W(v) mice lacking ICC. However, mast cells, which play critical roles in regula...

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Detalles Bibliográficos
Autores principales: Winston, John H., Chen, Jinghong, Shi, Xuan-Zheng, Sarna, Sushil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912454/
https://www.ncbi.nlm.nih.gov/pubmed/24550836
http://dx.doi.org/10.3389/fphys.2014.00022