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Hes1 is involved in the self-renewal and tumourigenicity of stem-like cancer cells in colon cancer

A small subpopulation of cancer cells with stem cell-like features might be responsible for tumour generation, progression, and chemoresistance. Hes1 influences the maintenance of certain stem cells and progenitor cells and the digestive systems. We found upregulated Hes1 in poorly differentiated ca...

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Detalles Bibliográficos
Autores principales: Gao, Fei, Zhang, YuQin, Wang, ShengChun, Liu, YuanQiang, Zheng, Lin, Yang, JianQuan, Huang, Wei, Ye, YanFen, Luo, WeiRen, Xiao, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912485/
https://www.ncbi.nlm.nih.gov/pubmed/24492635
http://dx.doi.org/10.1038/srep03963