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KIF13B enhances the endocytosis of LRP1 by recruiting LRP1 to caveolae

Multifunctional low-density lipoprotein (LDL) receptor-related protein 1 (LRP1) recognizes and internalizes a large number of diverse ligands, including LDL and factor VIII. However, little is known about the regulation of LRP1 endocytosis. Here, we show that a microtubule-based motor protein, KIF13...

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Detalles Bibliográficos
Autores principales: Kanai, Yoshimitsu, Wang, Daliang, Hirokawa, Nobutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912526/
https://www.ncbi.nlm.nih.gov/pubmed/24469637
http://dx.doi.org/10.1083/jcb.201309066