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The composition of EphB2 clusters determines the strength in the cellular repulsion response

Trans interactions of erythropoietin-producing human hepatocellular (Eph) receptors with their membrane-bound ephrin ligands generate higher-order clusters that can form extended signaling arrays. The functional relevance of the cluster size for repulsive signaling is not understood. We used chemica...

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Detalles Bibliográficos
Autores principales: Schaupp, Andreas, Sabet, Ola, Dudanova, Irina, Ponserre, Marion, Bastiaens, Philippe, Klein, Rüdiger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912530/
https://www.ncbi.nlm.nih.gov/pubmed/24469634
http://dx.doi.org/10.1083/jcb.201305037