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Anti-anxiety effect of a novel 5-HT(3) receptor antagonist N-(benzo[d]thiazol-2-yl)-3-ethoxyquinoxalin-2-carboxamide (6k) using battery tests for anxiety in mice

OBJECTIVE: To investigate the anti-anxiety activity of “6k”, a novel 5-hydroxytryptamine type 3 (5-HT(3)) receptor antagonist in in mice. MATERIALS AND METHODS: Anti-anxiety activity of “6k” (1, 2, and 4 mg/kg, intraperitoneally (i.p.)) was evaluated in mice by behavioral tests such as elevated plus...

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Detalles Bibliográficos
Autores principales: Kurhe, Yeshwant Vijay, Radhakrishnan, Mahesh, Thangaraj, Devadoss, Gupta, Deepali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912791/
https://www.ncbi.nlm.nih.gov/pubmed/24550593
http://dx.doi.org/10.4103/0253-7613.125186