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Neprilysin Is Poorly Expressed in the Prefrontal Cortex of Aged Dogs with Cognitive Dysfunction Syndrome

Neprilysin (NEP) is the principal amyloid β (Aβ) degrading peptidase; this activity may protect against Alzheimer's disease (AD), the most important age-related neurodegenerative process. The aim of this work was to analyze NEP mRNA expression in the frontal cortex of dogs with and without cani...

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Detalles Bibliográficos
Autores principales: Canudas, Jesús, Insua, Daniel, Sarasa, Leticia, González-Martínez, Ángela, Suárez, María Luisa, Santamarina, Germán, Pesini, Pedro, Sarasa, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912887/
https://www.ncbi.nlm.nih.gov/pubmed/24511411
http://dx.doi.org/10.1155/2014/483281