Induced ectopic expression of HigB toxin in Mycobacterium tuberculosis results in growth inhibition, reduced abundance of a subset of mRNAs and cleavage of tmRNA

In Mycobacterium tuberculosis, the genes Rv1954A–Rv1957 form an operon that includes Rv1955 and Rv1956 which encode the HigB toxin and the HigA antitoxin respectively. We are interested in the role and regulation of this operon, since toxin–antitoxin systems have been suggested to play a part in the...

Descripción completa

Detalles Bibliográficos
Autores principales: Schuessler, Dorothée L, Cortes, Teresa, Fivian-Hughes, Amanda S, Lougheed, Kathryn E A, Harvey, Evelyn, Buxton, Roger S, Davis, Elaine O, Young, Douglas B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Ltd 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912914/
https://www.ncbi.nlm.nih.gov/pubmed/23927792
http://dx.doi.org/10.1111/mmi.12358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912914/
https://www.ncbi.nlm.nih.gov/pubmed/23927792
http://dx.doi.org/10.1111/mmi.12358

Ejemplares similares