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The histone H3-K27 demethylase Utx regulates HOX gene expression in Drosophila in a temporally restricted manner
Trimethylation of histone H3 at lysine 27 (H3-K27me3) by Polycomb repressive complex 2 (PRC2) is a key step for transcriptional repression by the Polycomb system. Demethylation of H3-K27me3 by Utx and/or its paralogs has consequently been proposed to be important for counteracting Polycomb repressio...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Company of Biologists
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912917/ https://www.ncbi.nlm.nih.gov/pubmed/23900545 http://dx.doi.org/10.1242/dev.097204 |