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Arf1/COPI machinery acts directly on lipid droplets and enables their connection to the ER for protein targeting

Lipid droplets (LDs) are ubiquitous organelles that store neutral lipids, such as triacylglycerol (TG), as reservoirs of metabolic energy and membrane precursors. The Arf1/COPI protein machinery, known for its role in vesicle trafficking, regulates LD morphology, targeting of specific proteins to LD...

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Detalles Bibliográficos
Autores principales: Wilfling, Florian, Thiam, Abdou Rachid, Olarte, Maria-Jesus, Wang, Jing, Beck, Rainer, Gould, Travis J, Allgeyer, Edward S, Pincet, Frederic, Bewersdorf, Jörg, Farese, Robert V, Walther, Tobias C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913038/
https://www.ncbi.nlm.nih.gov/pubmed/24497546
http://dx.doi.org/10.7554/eLife.01607