Cargando…
Arf1/COPI machinery acts directly on lipid droplets and enables their connection to the ER for protein targeting
Lipid droplets (LDs) are ubiquitous organelles that store neutral lipids, such as triacylglycerol (TG), as reservoirs of metabolic energy and membrane precursors. The Arf1/COPI protein machinery, known for its role in vesicle trafficking, regulates LD morphology, targeting of specific proteins to LD...
Autores principales: | Wilfling, Florian, Thiam, Abdou Rachid, Olarte, Maria-Jesus, Wang, Jing, Beck, Rainer, Gould, Travis J, Allgeyer, Edward S, Pincet, Frederic, Bewersdorf, Jörg, Farese, Robert V, Walther, Tobias C |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913038/ https://www.ncbi.nlm.nih.gov/pubmed/24497546 http://dx.doi.org/10.7554/eLife.01607 |
Ejemplares similares
-
The Energy of COPI for Budding Membranes
por: Thiam, Abdou Rachid, et al.
Publicado: (2015) -
Mechanism of ribosome rescue by ArfA and RF2
por: Demo, Gabriel, et al.
Publicado: (2017) -
Pre-existing bilayer stresses modulate triglyceride accumulation in the ER versus lipid droplets
por: Zoni, Valeria, et al.
Publicado: (2021) -
Making Droplet-Embedded Vesicles to Model Cellular Lipid Droplets
por: Chorlay, Aymeric, et al.
Publicado: (2020) -
Neutral lipids regulate amphipathic helix affinity for model lipid droplets
por: Chorlay, Aymeric, et al.
Publicado: (2020)