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Molecular genetic tests for JAK2V617F, Exon12_JAK2 and MPLW515K/L are highly informative in the evaluation of patients suspected to have BCR-ABL1-negative myeloproliferative neoplasms

Polycythaemia vera (PV), essential thrombocythemia (ET) and idiopathic myelofibrosis (MF), are the most common myeloproliferative neoplasms (MPN) in patients without the BCR-ABL1 gene rearrangement. They are caused by clonal expansion of haematopoietic stem cells and share, as a diagnostic criterion...

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Detalles Bibliográficos
Autores principales: dos Santos, Marcos Tadeu, Mitne-Neto, Miguel, Miyashiro, Kozue, Chauffaille, Maria de Lourdes L Ferrari, Rizzatti, Edgar Gil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913116/
https://www.ncbi.nlm.nih.gov/pubmed/23986553
http://dx.doi.org/10.1136/jclinpath-2013-201822