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Ligand determinants of fatty acid activation of the pronociceptive ion channel TRPA1

Background and purpose. Arachidonic acid (AA) and its derivatives are important modulators of cellular signalling. The transient receptor potential cation channel subfamily A, member 1 (TRPA1) is a cation channel with important functions in mediating cellular responses to noxious stimuli and inflamm...

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Detalles Bibliográficos
Autores principales: Redmond, William John, Gu, Liuqiong, Camo, Maxime, McIntyre, Peter, Connor, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913255/
https://www.ncbi.nlm.nih.gov/pubmed/24516781
http://dx.doi.org/10.7717/peerj.248