Cargando…
Ligand determinants of fatty acid activation of the pronociceptive ion channel TRPA1
Background and purpose. Arachidonic acid (AA) and its derivatives are important modulators of cellular signalling. The transient receptor potential cation channel subfamily A, member 1 (TRPA1) is a cation channel with important functions in mediating cellular responses to noxious stimuli and inflamm...
Autores principales: | Redmond, William John, Gu, Liuqiong, Camo, Maxime, McIntyre, Peter, Connor, Mark |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913255/ https://www.ncbi.nlm.nih.gov/pubmed/24516781 http://dx.doi.org/10.7717/peerj.248 |
Ejemplares similares
-
Nordihydroguaiaretic acid activates hTRPA1 and modulates behavioral responses to noxious cold in mice
por: Redmond, William John, et al.
Publicado: (2014) -
Polyunsaturated fatty acids inhibit a pentameric ligand-gated ion channel through one of two binding sites
por: Dietzen, Noah M, et al.
Publicado: (2022) -
Atomic mutagenesis in ion channels with engineered stoichiometry
por: Lueck, John D, et al.
Publicado: (2016) -
A family of fluoride-specific ion channels with dual-topology architecture
por: Stockbridge, Randy B, et al.
Publicado: (2013) -
Excessive dietary linoleic acid promotes plasma accumulation of pronociceptive fatty acyl lipid mediators
por: Birkic, Nada, et al.
Publicado: (2022)