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RNAi-Mediated Knockdown of IKK1 in Transgenic Mice Using a Transgenic Construct Containing the Human H1 Promoter

Inhibition of gene expression through siRNAs is a tool increasingly used for the study of gene function in model systems, including transgenic mice. To achieve perdurable effects, the stable expression of siRNAs by an integrated transgenic construct is necessary. For transgenic siRNA expression, pro...

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Detalles Bibliográficos
Autores principales: Moreno-Maldonado, Rodolfo, Murillas, Rodolfo, Navarro, Manuel, Page, Angustias, Suarez-Cabrera, Cristian, Alameda, Josefa P., Bravo, Ana, Casanova, M. Llanos, Ramirez, Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913291/
https://www.ncbi.nlm.nih.gov/pubmed/24523631
http://dx.doi.org/10.1155/2014/193803