MG132 Ameliorates Kidney Lesions by Inhibiting the Degradation of Smad7 in Streptozotocin-Induced Diabetic Nephropathy

Background. Smad7 is the main negative regulatory protein in the transforming growth factor-β (TGF-β) downstream signaling pathway, which plays an important role in diabetic nephropathy (DN) and may be related to the ubiquitin proteasome pathway (UPP). Aim. We investigated the role of UPP in regulat...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Chenlin, Aqie, Keri, Zhu, Jianhua, Chen, Guo, Xu, Ling, Jiang, Lan, Xu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913347/
https://www.ncbi.nlm.nih.gov/pubmed/24511554
http://dx.doi.org/10.1155/2014/918396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913347/
https://www.ncbi.nlm.nih.gov/pubmed/24511554
http://dx.doi.org/10.1155/2014/918396

Ejemplares similares