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Anticonvulsant Potential of Certain New (2E)-2-[1-Aryl-3-(1H-imidazol-1-yl)propylidene]-N-(aryl/H)hydrazinecarboxamides

Anticonvulsant potential and neurotoxicity of certain new imidazole-containing arylsemicarbazones 6a–p are reported. The test compounds 6a–p exhibited anticonvulsant activity mainly in the scPTZ screen. Compound 6p emerged as the most active surrogate displaying 100% protection at a dose level of 63...

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Detalles Bibliográficos
Autores principales: Attia, Mohamed I., Aboul-Enein, Mohamed N., El-Azzouny, Aida A., Maklad, Yousreya A., Ghabbour, Hazem A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913509/
https://www.ncbi.nlm.nih.gov/pubmed/24523636
http://dx.doi.org/10.1155/2014/357403