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Construction of Drug Network Based on Side Effects and Its Application for Drug Repositioning
Drugs with similar side-effect profiles may share similar therapeutic properties through related mechanisms of action. In this study, a drug-drug network was constructed based on the similarities between their clinical side effects. The indications of a drug may be inferred by the enriched FDA-appro...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913703/ https://www.ncbi.nlm.nih.gov/pubmed/24505324 http://dx.doi.org/10.1371/journal.pone.0087864 |