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Construction of Drug Network Based on Side Effects and Its Application for Drug Repositioning

Drugs with similar side-effect profiles may share similar therapeutic properties through related mechanisms of action. In this study, a drug-drug network was constructed based on the similarities between their clinical side effects. The indications of a drug may be inferred by the enriched FDA-appro...

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Detalles Bibliográficos
Autores principales: Ye, Hao, Liu, Qi, Wei, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913703/
https://www.ncbi.nlm.nih.gov/pubmed/24505324
http://dx.doi.org/10.1371/journal.pone.0087864