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Loss of Igfbp7 Causes Precocious Involution in Lactating Mouse Mammary Gland

BACKGROUND: Insulin like growth factors (IGFs) and their binding proteins (IGFBPs) are secreted peptides that play major roles in regulating the normal development and maturation of mammary gland. While Igfbp7 has been shown to decrease breast tumor growth, its role in regulating the normal mammary...

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Detalles Bibliográficos
Autores principales: Chatterjee, Sumanta, Bacopulos, Stephanie, Yang, Wenyi, Amemiya, Yutaka, Spyropoulos, Demetri, Raouf, Afshin, Seth, Arun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913705/
https://www.ncbi.nlm.nih.gov/pubmed/24505323
http://dx.doi.org/10.1371/journal.pone.0087858