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Loss of Igfbp7 Causes Precocious Involution in Lactating Mouse Mammary Gland
BACKGROUND: Insulin like growth factors (IGFs) and their binding proteins (IGFBPs) are secreted peptides that play major roles in regulating the normal development and maturation of mammary gland. While Igfbp7 has been shown to decrease breast tumor growth, its role in regulating the normal mammary...
Autores principales: | Chatterjee, Sumanta, Bacopulos, Stephanie, Yang, Wenyi, Amemiya, Yutaka, Spyropoulos, Demetri, Raouf, Afshin, Seth, Arun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913705/ https://www.ncbi.nlm.nih.gov/pubmed/24505323 http://dx.doi.org/10.1371/journal.pone.0087858 |
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