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Corticotropin-Releasing Factor Facilitates Epileptiform Activity in the Entorhinal Cortex: Roles of CRF(2) Receptors and PKA Pathway

Whereas corticotropin-releasing factor (CRF) has been considered as the most potent epileptogenic neuropeptide in the brain, its action site and underlying mechanisms in epilepsy have not been determined. Here, we found that the entorhinal cortex (EC) expresses high level of CRF and CRF(2) receptors...

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Detalles Bibliográficos
Autores principales: Kurada, Lalitha, Yang, Chuanxiu, Lei, Saobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913751/
https://www.ncbi.nlm.nih.gov/pubmed/24505399
http://dx.doi.org/10.1371/journal.pone.0088109