Escherichia coli Deletion Mutants Illuminate Trade-Offs between Growth Rate and Flux through a Foreign Anabolic Pathway

Metabolic engineers strive to improve the production yields of microbial fermentations, sometimes by mutating the genomes of production strains. Some mutations are detrimental to the health of the organism, so a quantitative and mechanistic understanding of the trade-offs could inform better designs...

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Detalles Bibliográficos
Autores principales: Falls, Kelly C., Williams, Aimee L., Bryksin, Anton V., Matsumura, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913754/
https://www.ncbi.nlm.nih.gov/pubmed/24505410
http://dx.doi.org/10.1371/journal.pone.0088159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913754/
https://www.ncbi.nlm.nih.gov/pubmed/24505410
http://dx.doi.org/10.1371/journal.pone.0088159

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