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Synergistic cytotoxicity of gemcitabine, clofarabine and edelfosine in lymphoma cell lines
Treatments for lymphomas include gemcitabine (Gem) and clofarabine (Clo) which inhibit DNA synthesis. To improve their cytotoxicity, we studied their synergism with the alkyl phospholipid edelfosine (Ed). Exposure of the J45.01 and SUP-T1 (T-cell) and the OCI-LY10 (B-cell) lymphoma cell lines to IC(...
Autores principales: | Valdez, B C, Zander, A R, Song, G, Murray, D, Nieto, Y, Li, Y, Champlin, R E, Andersson, B S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913938/ https://www.ncbi.nlm.nih.gov/pubmed/24413065 http://dx.doi.org/10.1038/bcj.2013.69 |
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