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Dynamics of ASXL1 mutation and other associated genetic alterations during disease progression in patients with primary myelodysplastic syndrome

Recently, mutations of the additional sex comb-like 1 (ASXL1) gene were identified in patients with myelodysplastic syndrome (MDS), but the interaction of this mutation with other genetic alterations and its dynamic changes during disease progression remain to be determined. In this study, ASXL1 mut...

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Detalles Bibliográficos
Autores principales: Chen, T-C, Hou, H-A, Chou, W-C, Tang, J-L, Kuo, Y-Y, Chen, C-Y, Tseng, M-H, Huang, C-F, Lai, Y-J, Chiang, Y-C, Lee, F-Y, Liu, M-C, Liu, C-W, Liu, C-Y, Yao, M, Huang, S-Y, Ko, B-S, Hsu, S-C, Wu, S-J, Tsay, W, Chen, Y-C, Tien, H-F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913943/
https://www.ncbi.nlm.nih.gov/pubmed/24442206
http://dx.doi.org/10.1038/bcj.2013.74