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Ibrutinib for B cell malignancies

Research over the role of Bruton’s agammaglobulinemia tyrosine kinase (BTK) in B-lymphocyte development, differentiation, signaling and survival has led to better understanding of the pathogenesis of B-cell malignancies. Down-regulation of BTK activity is an attractive novel strategy for treating pa...

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Detalles Bibliográficos
Autores principales: Novero, Aileen, Ravella, Pavan M, Chen, Yamei, Dous, George, Liu, Delong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913970/
https://www.ncbi.nlm.nih.gov/pubmed/24472371
http://dx.doi.org/10.1186/2162-3619-3-4