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Developmental and maintenance defects in Rett syndrome neurons identified by a new mouse staging system in vitro
Rett Syndrome (RTT) is a neurodevelopmental disorder associated with intellectual disability, mainly caused by loss-of-function mutations in the MECP2 gene. RTT brains display decreased neuronal size and dendritic arborization possibly caused by either a developmental failure or a deficit in the mai...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914021/ https://www.ncbi.nlm.nih.gov/pubmed/24550777 http://dx.doi.org/10.3389/fncel.2014.00018 |