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Developmental and maintenance defects in Rett syndrome neurons identified by a new mouse staging system in vitro

Rett Syndrome (RTT) is a neurodevelopmental disorder associated with intellectual disability, mainly caused by loss-of-function mutations in the MECP2 gene. RTT brains display decreased neuronal size and dendritic arborization possibly caused by either a developmental failure or a deficit in the mai...

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Detalles Bibliográficos
Autores principales: Baj, Gabriele, Patrizio, Angela, Montalbano, Alberto, Sciancalepore, Marina, Tongiorgi, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914021/
https://www.ncbi.nlm.nih.gov/pubmed/24550777
http://dx.doi.org/10.3389/fncel.2014.00018