Electrophysiological biomarkers in spinal muscular atrophy: proof of concept

OBJECTIVE: Preclinical therapies that restore survival motor neuron (SMN) protein levels can dramatically extend survival in spinal muscular atrophy (SMA) mouse models. Biomarkers are needed to effectively translate these promising therapies to clinical trials. Our objective was to investigate elect...

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Detalles Bibliográficos
Autores principales: David Arnold, W, Porensky, Paul N, McGovern, Vicki L, Iyer, Chitra C, Duque, Sandra, Li, Xiaobai, Meyer, Kathrin, Schmelzer, Leah, Kaspar, Brian K, Kolb, Stephen J, Kissel, John T, Burghes, Arthur H M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914317/
https://www.ncbi.nlm.nih.gov/pubmed/24511555
http://dx.doi.org/10.1002/acn3.23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914317/
https://www.ncbi.nlm.nih.gov/pubmed/24511555
http://dx.doi.org/10.1002/acn3.23

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