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AR-A 014418 Used against GSK3beta Downregulates Expression of hnRNPA1 and SF2/ASF Splicing Factors

Glioblastoma is one of the most aggressive forms of primary brain tumors of glial cells, including aberrant regulation of glycogen synthase kinase 3β (GSK3β) and splicing factors deregulation. Here, we investigate the role of small molecule AR-A014418 and Manzamine A against GSK3 kinase with factual...

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Detalles Bibliográficos
Autores principales: Yadav, Ajay K., Vashishta, Vidhi, Joshi, Nidhi, Taneja, Pankaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914408/
https://www.ncbi.nlm.nih.gov/pubmed/24550987
http://dx.doi.org/10.1155/2014/695325