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Pioglitazone Upregulates Angiotensin Converting Enzyme 2 Expression in Insulin-Sensitive Tissues in Rats with High-Fat Diet-Induced Nonalcoholic Steatohepatitis

Background and Aim. Thiazolidinediones (TZDs) can improve hepatic steatosis in nonalcoholic steatohepatitis (NASH). Angiotensin (Ang) II, the primary effector of renin-angiotensin system (RAS), plays vital roles in the development and progression of NASH. And some AngII-mediated effects can be regul...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Xu, Yi-Zhi, Liu, Bo, Wu, Rong, Yang, Ying-Ying, Xiao, Xiao-Qiu, Zhang, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914411/
https://www.ncbi.nlm.nih.gov/pubmed/24558317
http://dx.doi.org/10.1155/2014/603409