Customizing the Therapeutic Response of Signaling Networks to Promote Antitumor Responses by Drug Combinations

Drug resistance, de novo and acquired, pervades cellular signaling networks (SNs) from one signaling motif to another as a result of cancer progression and/or drug intervention. This resistance is one of the key determinants of efficacy in targeted anti-cancer drug therapy. Although poorly understoo...

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Detalles Bibliográficos
Autores principales: Goltsov, Alexey, Langdon, Simon P., Goltsov, Gregory, Harrison, David J., Bown, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914444/
https://www.ncbi.nlm.nih.gov/pubmed/24551596
http://dx.doi.org/10.3389/fonc.2014.00013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914444/
https://www.ncbi.nlm.nih.gov/pubmed/24551596
http://dx.doi.org/10.3389/fonc.2014.00013

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