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Customizing the Therapeutic Response of Signaling Networks to Promote Antitumor Responses by Drug Combinations
Drug resistance, de novo and acquired, pervades cellular signaling networks (SNs) from one signaling motif to another as a result of cancer progression and/or drug intervention. This resistance is one of the key determinants of efficacy in targeted anti-cancer drug therapy. Although poorly understoo...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914444/ https://www.ncbi.nlm.nih.gov/pubmed/24551596 http://dx.doi.org/10.3389/fonc.2014.00013 |