Stimulation of Neural Stem Cell Proliferation by Inhibition of Phosphodiesterase 5

The involvement of nitric oxide (NO) and cyclic GMP (cGMP) in neurogenesis has been progressively unmasked over the last decade. Phosphodiesterase 5 (PDE5) specifically degrades cGMP and is highly abundant in the mammalian brain. Inhibition of cGMP hydrolysis by blocking PDE5 is a possible strategy...

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Detalles Bibliográficos
Autores principales: Santos, Ana I., Carreira, Bruno P., Nobre, Rui J., Carvalho, Caetana M., Araújo, Inês M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914480/
https://www.ncbi.nlm.nih.gov/pubmed/24550991
http://dx.doi.org/10.1155/2014/878397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914480/
https://www.ncbi.nlm.nih.gov/pubmed/24550991
http://dx.doi.org/10.1155/2014/878397

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