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The CCN Family Proteins: Modulators of Bone Development and Novel Targets in Bone-Associated Tumors
The CCN family of proteins is composed of six extracellular matrix-associated proteins that play crucial roles in skeletal development, wound healing, fibrosis, and cancer. Members of the CCN family share four conserved cysteine-rich modular domains that trigger signal transduction in cell adhesion,...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914550/ https://www.ncbi.nlm.nih.gov/pubmed/24551846 http://dx.doi.org/10.1155/2014/437096 |