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Angiotensin II type 2 receptor correlates with therapeutic effects of losartan in rats with adjuvant-induced arthritis

The angiotensin II type 1 receptor (AT1R) blocker losartan ameliorates rheumatoid arthritis (RA) in an experimental model. In RA, AT2R mainly opposes AT1R, but the mechanism by which this occurs still remains obscure. In the present study, we investigated the role of AT2R in the treatment of rats wi...

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Detalles Bibliográficos
Autores principales: Wang, Di, Hu, Shanshan, Zhu, Jie, Yuan, Jun, Wu, Jingjing, Zhou, Aiwu, Wu, Yujing, Zhao, Wendi, Huang, Qiong, Chang, Yan, Wang, Qingtong, Sun, Wuyi, Wei, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914644/
https://www.ncbi.nlm.nih.gov/pubmed/24112447
http://dx.doi.org/10.1111/jcmm.12128