Matrix metalloproteinase inhibition attenuates right ventricular dysfunction and improves responses to dobutamine during acute pulmonary thromboembolism

Activated matrix metalloproteinases (MMPs) cause cardiomyocyte injury during acute pulmonary thromboembolism (APT). However, the functional consequences of this alteration are not known. We examined whether doxycycline (a MMP inhibitor) improves right ventricle function and the cardiac responses to...

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Detalles Bibliográficos
Autores principales: Neto-Neves, Evandro M, Sousa-Santos, Ozelia, Ferraz, Karina C, Rizzi, Elen, Ceron, Carla S, Romano, Minna M D, Gali, Luis G, Maciel, Benedito C, Schulz, Richard, Gerlach, Raquel F, Tanus-Santos, Jose E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Ltd 2013
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914650/
https://www.ncbi.nlm.nih.gov/pubmed/24199964
http://dx.doi.org/10.1111/jcmm.12163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914650/
https://www.ncbi.nlm.nih.gov/pubmed/24199964
http://dx.doi.org/10.1111/jcmm.12163

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