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Development and Validation of a Gene Expression Score That Predicts Response to Fulvestrant in Breast Cancer Patients

Fulvestrant is a selective estrogen receptor antagonist. Based on the measured growth inhibition of 60 human cancer cell lines (NCI60) in the presence of fulvestrant, as well as the baseline gene expression of the 60 cell lines, a gene expression score that predicts response to fulvestrant was devel...

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Detalles Bibliográficos
Autores principales: Knudsen, Steen, Jensen, Thomas, Hansen, Anker, Mazin, Wiktor, Lindemann, Justin, Kuter, Irene, Laing, Naomi, Anderson, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914825/
https://www.ncbi.nlm.nih.gov/pubmed/24505287
http://dx.doi.org/10.1371/journal.pone.0087415