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Development and Validation of a Gene Expression Score That Predicts Response to Fulvestrant in Breast Cancer Patients
Fulvestrant is a selective estrogen receptor antagonist. Based on the measured growth inhibition of 60 human cancer cell lines (NCI60) in the presence of fulvestrant, as well as the baseline gene expression of the 60 cell lines, a gene expression score that predicts response to fulvestrant was devel...
Autores principales: | Knudsen, Steen, Jensen, Thomas, Hansen, Anker, Mazin, Wiktor, Lindemann, Justin, Kuter, Irene, Laing, Naomi, Anderson, Elizabeth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914825/ https://www.ncbi.nlm.nih.gov/pubmed/24505287 http://dx.doi.org/10.1371/journal.pone.0087415 |
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