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A Novel Cellular Senescence Gene, SENEX, Is Involved in Peripheral Regulatory T Cells Accumulation in Aged Urinary Bladder Cancer

Regulatory T cells (Tregs) play an essential role in sustaining self-tolerance and immune homeostasis. Despite many studies on the correlation between Tregs accumulation and age, or malignancies, the related mechanism hasn’t been well explored. To find out the mechanism of Tregs accumulation in aged...

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Detalles Bibliográficos
Autores principales: Chen, Tianping, Wang, Huiping, Zhang, Zhiqiang, Li, Qing, Yan, Kaili, Tao, Qianshan, Ye, Qianling, Xiong, Shudao, Wang, Yiping, Zhai, Zhimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914842/
https://www.ncbi.nlm.nih.gov/pubmed/24505313
http://dx.doi.org/10.1371/journal.pone.0087774