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Supporting a Role for the GTPase Rab7 in Prostate Cancer Progression

Invasion and subsequent metastasis is the major cause of death from most cancers including prostate cancer. Herein we report on the potential tumor suppressive properties of Rab7, a GTPase that regulates trafficking of lysosomes. The movement of lysosomes to the cell surface in response to environme...

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Detalles Bibliográficos
Autores principales: Steffan, Joshua J., Dykes, Samantha S., Coleman, David T., Adams, Lisa K., Rogers, Donna, Carroll, Jennifer L., Williams, B. Jill, Cardelli, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914878/
https://www.ncbi.nlm.nih.gov/pubmed/24505328
http://dx.doi.org/10.1371/journal.pone.0087882