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Decreased PGE(2) Content Reduces MMP-1 Activity and Consequently Increases Collagen Density in Human Varicose Vein
Varicose veins are elongated and dilated saphenous veins. Despite the high prevalence of this disease, its pathogenesis remains unclear. AIMS: In this study, we investigated the control of matrix metalloproteinases (MMPs) expression by prostaglandin (PG)E(2) during the vascular wall remodeling of hu...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914898/ https://www.ncbi.nlm.nih.gov/pubmed/24505358 http://dx.doi.org/10.1371/journal.pone.0088021 |