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Decreased PGE(2) Content Reduces MMP-1 Activity and Consequently Increases Collagen Density in Human Varicose Vein

Varicose veins are elongated and dilated saphenous veins. Despite the high prevalence of this disease, its pathogenesis remains unclear. AIMS: In this study, we investigated the control of matrix metalloproteinases (MMPs) expression by prostaglandin (PG)E(2) during the vascular wall remodeling of hu...

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Detalles Bibliográficos
Autores principales: Gomez, Ingrid, Benyahia, Chabha, Louedec, Liliane, Leséche, Guy, Jacob, Marie-Paule, Longrois, Dan, Norel, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914898/
https://www.ncbi.nlm.nih.gov/pubmed/24505358
http://dx.doi.org/10.1371/journal.pone.0088021