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Sulindac Compounds Facilitate the Cytotoxicity of β-Lapachone by Up-Regulation of NAD(P)H Quinone Oxidoreductase in Human Lung Cancer Cells

β-lapachone, a major component in an ethanol extract of Tabebuia avellanedae bark, is a promising potential therapeutic drug for various tumors, including lung cancer, the leading cause of cancer-related deaths worldwide. In the first part of this study, we found that apoptotic cell death induced in...

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Detalles Bibliográficos
Autores principales: Kung, Hsiu-Ni, Weng, Tsai-Yun, Liu, Yu-Lin, Lu, Kuo-Shyan, Chau, Yat-Pang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914905/
https://www.ncbi.nlm.nih.gov/pubmed/24505400
http://dx.doi.org/10.1371/journal.pone.0088122