SEC14 and Spectrin Domains 1 (Sestd1), Dishevelled 2 (Dvl2) and Dapper Antagonist of Catenin-1 (Dact1) co-regulate the Wnt/Planar Cell Polarity (PCP) pathway during mammalian development

We previously reported that Sestd1 KO phenocopies Dact1 KO in mice, consistent with a model in which Sestd1 and Dact1 act together to form a crucial functional complex that regulates Vangl2 in the Wnt/Planar Cell Polarity (PCP) pathway. Here, we show that Dvl2, a binding partner of Dact1, also forms...

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Detalles Bibliográficos
Autores principales: Yang, XiaoYong, Fisher, Daniel A, Cheyette, Benjamin NR
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914910/
https://www.ncbi.nlm.nih.gov/pubmed/24505507
http://dx.doi.org/10.4161/cib.26834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914910/
https://www.ncbi.nlm.nih.gov/pubmed/24505507
http://dx.doi.org/10.4161/cib.26834

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