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Optimal CD4 Count for Initiating HIV Treatment: Impact of CD4 Observation Frequency and Grace Periods, and Performance of Dynamic Marginal Structural Models
BACKGROUND: In HIV infection, dynamic marginal structural models have estimated the optimal CD4 for treatment initiation to minimize AIDS/death. The impact of CD4 observation frequency and grace periods (permitted delay to initiation) on the optimal regimen has not been investigated nor has the perf...
Autores principales: | Ewings, Fiona M., Ford, Deborah, Walker, A. Sarah, Carpenter, James, Copas, Andrew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914951/ https://www.ncbi.nlm.nih.gov/pubmed/24487204 http://dx.doi.org/10.1097/EDE.0000000000000043 |
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