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Residual Viremia in an RT-SHIV Rhesus Macaque HAART Model Marked by the Presence of a Predominant Plasma Clone and a Lack of Viral Evolution

Highly active antiretroviral therapy (HAART) significantly reduces HIV-1 replication and prevents progression to AIDS. However, residual low-level viremia (LLV) persists and long-lived viral reservoirs are maintained in anatomical sites. These reservoirs permit a recrudescence of viremia upon cessat...

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Detalles Bibliográficos
Autores principales: Kauffman, Robert C., Villalobos, Andradi, Bowen, Joanne H., Adamson, Lourdes, Schinazi, Raymond F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914964/
https://www.ncbi.nlm.nih.gov/pubmed/24505452
http://dx.doi.org/10.1371/journal.pone.0088258