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Residual Viremia in an RT-SHIV Rhesus Macaque HAART Model Marked by the Presence of a Predominant Plasma Clone and a Lack of Viral Evolution
Highly active antiretroviral therapy (HAART) significantly reduces HIV-1 replication and prevents progression to AIDS. However, residual low-level viremia (LLV) persists and long-lived viral reservoirs are maintained in anatomical sites. These reservoirs permit a recrudescence of viremia upon cessat...
Autores principales: | Kauffman, Robert C., Villalobos, Andradi, Bowen, Joanne H., Adamson, Lourdes, Schinazi, Raymond F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914964/ https://www.ncbi.nlm.nih.gov/pubmed/24505452 http://dx.doi.org/10.1371/journal.pone.0088258 |
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