Combination of (1)H NMR- and GC-MS-Based Metabonomics to Study on the Toxicity of Coptidis Rhizome in Rats

BACKGROUND: Coptidis Rhizome (CR), widely applied to treat with heat and toxicity, is one of the most commonly used traditional Chinese medicine (TCM), however, an extensive dosage can induce toxicity. Diarrhea is one of the most frequent side effects of CR treatment. METHODOLOGY/PRINCIPAL FINDINGS:...

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Detalles Bibliográficos
Autores principales: Zhou, Yuting, Liao, Qiongfeng, Lin, Manna, Deng, Xuejiao, Zhang, Peiting, Yao, Meicun, Zhang, Lei, Xie, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914965/
https://www.ncbi.nlm.nih.gov/pubmed/24505462
http://dx.doi.org/10.1371/journal.pone.0088281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914965/
https://www.ncbi.nlm.nih.gov/pubmed/24505462
http://dx.doi.org/10.1371/journal.pone.0088281

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