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Combination of (1)H NMR- and GC-MS-Based Metabonomics to Study on the Toxicity of Coptidis Rhizome in Rats
BACKGROUND: Coptidis Rhizome (CR), widely applied to treat with heat and toxicity, is one of the most commonly used traditional Chinese medicine (TCM), however, an extensive dosage can induce toxicity. Diarrhea is one of the most frequent side effects of CR treatment. METHODOLOGY/PRINCIPAL FINDINGS:...
Autores principales: | Zhou, Yuting, Liao, Qiongfeng, Lin, Manna, Deng, Xuejiao, Zhang, Peiting, Yao, Meicun, Zhang, Lei, Xie, Zhiyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914965/ https://www.ncbi.nlm.nih.gov/pubmed/24505462 http://dx.doi.org/10.1371/journal.pone.0088281 |
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